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They inflict pain, lead to functional impairment and disability, and generate a massive financial burden for families and society ( Ferroptosis was proposed as a novel form of cell death in 2012

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Given that GSH has a molecular weight similar to that of amino acids, a plausible scenario is that when plants experience mechanical damage or insect attack, a large volume of GSH from the intracellular region may surge into the apoplastic region, inducing calcium influx by activation of the GLR3.3 ion channel